- "People tolerate me because Melissa is my sister, but to most of them, I am just that weird gay kid."
- —Isaac to Payton.
In order to hide his insecurities about his sexuality, Isaac adopted a very outspoken and flamboyant personality. However, he later admitted people only tolerated him because of his sister. Henry Mitchell Jr. was one of his few friends and Isaac later got involved with Payton Halliwell by helping her getting a new outfit for a party. They bonded over their shared insecurities and later became friends. Isaac took care of his sister after she was attacked by a mysterious figure and later told Payton she was fine.
Some time later, Isaac called Payton and asked her to meet him at the mall, as he needed a new outfit for a date. She told him that she was nervous about sleeping with Sean because she was still a virgin. Isaac advised her to talk to Sean about it, telling her that he didn't deserve her if he didn't want to wait.